Topoisomerase II brings about transient double-strand breaks during the twisting of two double-stranded DNA helices. Singleand double-stranded DNA breaks have been documented immediately after in vivo and in vitro procedure with doxorubicin of P388 leukaemia cells in mice[8]. Whilst less prevalent, one of the most significant Unwanted side effects of https://hansp888dnx0.eveowiki.com/user