Abstract The aim is to investigate the evidence for shared genetic architecture between each of asthma. allergic rhinitis and eczema with gastro-esophageal reflux disease (GERD). Structural equation models (SEM) and polygenic risk score (PRS) analyses are applied to three Swedish twin cohorts (n = 46. 582) and reveal a modest genetic correlation between GERD and asthma of 0. https://www.hindirochakkahaniya.com/