Pentobarbital will reduce the extent or effect of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. pentobarbital will raise the level or impact of ivosidenib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of ivosidenib with potent CYP3A4 inducers decreased ivosidenib plasma concentratio... https://what-kind-of-drug-is-nemb50481.thelateblog.com/31583557/everything-about-nembutal-was-ist-das