Evidence-based professional reference pages authored by our clinical team for the use of medical professionals. An acute exacerbation is more commonly known kakım a 'flare-up'. An acute exacerbation of chronic obstructive pulmonary disease (COPD) is a sudden worsening of COPD symptoms compared with the usual severity of symptoms. İnflamasyon (iltihap), https://jsfiddle.net/rubmiddle4/buxqa0oy/