Our new research show that this is because of faulty trafficking of late endosomes to lysosomes, with concomitant homotypic fusion of the afflicted vesicular compartments [five]. The defect in lysosome-directed trafficking also affects autophagic flux, with resultant accumulation of autophagosomes [5]. In the long run, the integrity of the cell https://michaell529fjn3.blog2freedom.com/profile