Substitution at R3 which has a halogen or alkoxy group (74f–74i) brought about a slight rise in cellular potency Using the halide analogs (74g–h) showing optimum the potency from the group. Even more optimization led to the invention of 74i–j, with 74k as probably the most Lively compound while in https://zanderjbpet.theisblog.com/31654677/5-essential-elements-for-indazole-3-carboxylic-acid